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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKD All Species: 10.61
Human Site: S582 Identified Species: 23.33
UniProt: Q16760 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16760 NP_003639.2 1214 134525 S582 E D G D G S G S I C G S T G D
Chimpanzee Pan troglodytes XP_001151474 1220 134870 G593 S S S E E S L G E S K E Q L V
Rhesus Macaque Macaca mulatta XP_001114920 1167 129871 S538 E D G D G S G S V C G S T G D
Dog Lupus familis XP_543293 1324 146248 S692 E D G D G A G S G C G S T G E
Cat Felis silvestris
Mouse Mus musculus NP_808314 1220 135190 N582 E D G D G S G N I C S S T G D
Rat Rattus norvegicus XP_347259 1196 133109 N562 E D G D G S G N I C S S T G D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507672 1254 138458 S623 D F S S E D S S L T D S K E Q
Chicken Gallus gallus XP_001232791 1333 149344 L700 E F S S E E S L S E S K E Q L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693512 1148 127826 S527 T K M L D R W S V M T Y E V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A8JQ65 1895 211641 I614 A Y L L N P N I S I E K T E K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202627 1158 127377 V520 G P S T S S R V F K P R D A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 65.2 93.4 85.1 N.A. 93.7 90.2 N.A. 66.9 63.9 N.A. 60.9 N.A. 34.8 N.A. N.A. 53.3
Protein Similarity: 100 76.3 94.1 87.8 N.A. 96.4 93.3 N.A. 77.4 73.8 N.A. 71.6 N.A. 46.5 N.A. N.A. 65.8
P-Site Identity: 100 6.6 93.3 80 N.A. 86.6 86.6 N.A. 13.3 6.6 N.A. 6.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 93.3 N.A. 93.3 93.3 N.A. 26.6 6.6 N.A. 13.3 N.A. 6.6 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 46 0 0 0 0 0 % C
% Asp: 10 46 0 46 10 10 0 0 0 0 10 0 10 0 37 % D
% Glu: 55 0 0 10 28 10 0 0 10 10 10 10 19 19 10 % E
% Phe: 0 19 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 10 0 46 0 46 0 46 10 10 0 28 0 0 46 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 28 10 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 0 10 10 19 10 0 10 % K
% Leu: 0 0 10 19 0 0 10 10 10 0 0 0 0 10 19 % L
% Met: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 10 19 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 10 0 0 0 0 10 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 10 % Q
% Arg: 0 0 0 0 0 10 10 0 0 0 0 10 0 0 0 % R
% Ser: 10 10 37 19 10 55 19 46 19 10 28 55 0 0 0 % S
% Thr: 10 0 0 10 0 0 0 0 0 10 10 0 55 0 0 % T
% Val: 0 0 0 0 0 0 0 10 19 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _